Genome-wide linkage scan of quantitative traits representing symptom dimensions in multiplex schizophrenia families
… of disease-susceptibility genes, or separate traits related to disease-modifier genes. …
symptom dimensions of schizophrenia through genome-wide quantitative trait locus (QTL) linkage …
symptom dimensions of schizophrenia through genome-wide quantitative trait locus (QTL) linkage …
[HTML][HTML] A genome-wide linkage scan for distinct subsets of schizophrenia characterized by age at onset and neurocognitive deficits
YJ Lien, PC Hsiao, CM Liu, SV Faraone, MT Tsuang… - PloS one, 2011 - journals.plos.org
… may reduce heterogeneity or represent the more direct effects of … of families of patients with
schizophrenia characterized by … sub-grouping by particular quantitative traits in these studies. …
schizophrenia characterized by … sub-grouping by particular quantitative traits in these studies. …
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia
ML Hamshere, PA Holmans… - American Journal of …, 2011 - Wiley Online Library
… and genome-wide covariate linkage analysis for symptom … join two nuclear families together
to create one larger family of … of linkage analysis were employed, the quantitative trait locus (…
to create one larger family of … of linkage analysis were employed, the quantitative trait locus (…
[HTML][HTML] Genome-wide linkage analyses of quantitative and categorical autism subphenotypes
XQ Liu, AD Paterson, P Szatmari… - Biological …, 2008 - Elsevier
… In this study, using 976 multiplex families from the Autism … both ASD and schizophrenia, for
example, association of gene … to different dimensions, so the quantitative traits we used may …
example, association of gene … to different dimensions, so the quantitative traits we used may …
Heritability of subcortical and limbic brain volume and shape in multiplex-multigenerational families with schizophrenia
… use of multiplex-multigenerational families is likely to represent a … multiplex-multigenerational
families with schizophrenia. Such localized features may be related to distinct dimensions …
families with schizophrenia. Such localized features may be related to distinct dimensions …
A quantitative trait locus analysis of social responsiveness in multiplex autism families
JA Duvall, A Lu, RM Cantor, RD Todd… - American Journal of …, 2007 - Am Psychiatric Assoc
… Alzheimer’s disease and schizophrenia is about 0.45% and … genome-wide linkage scan for
social quantitative trait loci in … research represents the first genome scan of core social traits …
social quantitative trait loci in … research represents the first genome scan of core social traits …
[PDF][PDF] Molecular genetics of schizophrenia and comorbid and related traits
J Ekelund - 2001 - julkari.fi
… a large number of families affected with schizophrenia. These … We performed a genome-wide
scan in a sib-pair collection … since the original cohort represents, without selection, all …
scan in a sib-pair collection … since the original cohort represents, without selection, all …
Molecular validation of the schizophrenia spectrum
… families of schizophrenic probands. Can we validate, using molecular polygene scores from
genome-wide association … from a subset of larger families and multiplex sibships. Third, the …
genome-wide association … from a subset of larger families and multiplex sibships. Third, the …
Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression
EEM Knowles, JW Kent Jr, DR McKay… - Journal of affective …, 2016 - Elsevier
… The present study combines family-based linkage with a … to be modeled as a unitary
quantitative trait. It is important to note … of this linkage signal originated from a single multiplex …
quantitative trait. It is important to note … of this linkage signal originated from a single multiplex …
A genome‐wide quantitative trait locus (QTL) linkage scan of NEO personality factors in Latino families segregating bipolar disorder
BD Lee, S Gonzalez, E Villa… - American Journal of …, 2017 - Wiley Online Library
… extended pedigrees originally ascertained for having multiplex cases of BP (963 cases of …
genome-wide suggestive cutoff (LOD scores >2.2) as determined for each triat are represented …
genome-wide suggestive cutoff (LOD scores >2.2) as determined for each triat are represented …